Common Anesthetic

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An anesthetic renders a creature immune to pain (suffering half subdual damage and a bonus against stunning attacks) but makes the body unresponsive (a penalty to Dexterity and unable to feel touch.) Each dose last only a few minutes[1]

References

Data from the Ravenloft Catalogue

Van Richten's Arsenal

Van Richten's Arsenal - p60

Van Richten's Arsenal - p58